Opportunity Information: Apply for RFA DP 18 001
The grant opportunity titled "Etiology and Outcome of Inflammatory Bowel Disease" (Funding Opportunity Number RFA DP 18 001) is a CDC cooperative agreement focused on improving the public health understanding of inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis. IBD is described as a chronic inflammatory condition of the gastrointestinal tract, and the announcement highlights its growing burden in the United States. It notes that about three million US adults reported an IBD diagnosis in 2015, up from an estimated 1.8 million in 1999, underscoring both rising prevalence and the expanding impact on patients and the healthcare system. While the precise cause of IBD remains unclear, the opportunity emphasizes that disease severity and progression can significantly reduce quality of life and create substantial financial costs across the healthcare landscape.
The core purpose of the funding is to build a stronger evidence base about how IBD starts, how it progresses over time, and how outcomes differ across populations and healthcare settings. A central deliverable is the establishment of a new IBD registry designed to estimate the incidence of IBD in both adult and pediatric populations and then extrapolate those incidence estimates to the broader US population. Beyond measuring incidence, the registry and associated work are intended to support a deeper description of the natural history of IBD, meaning how the disease develops, fluctuates, and leads to different long-term outcomes for patients. This includes tracking outcomes that may reflect disease complications, healthcare utilization patterns, and broader health effects tied to living with a chronic inflammatory condition.
Another major goal is to examine racial and ethnic variation in how IBD is detected and managed. This reflects an interest not only in biological or genetic differences, but also in potential differences driven by access to care, diagnostic practices, treatment patterns, healthcare delivery systems, and other social or structural factors that can shape whether IBD is recognized early, treated consistently, and managed according to best practices. By identifying and characterizing these variations, the work aims to clarify where inequities may exist and how they might influence patient outcomes.
The opportunity also calls for identifying evidence-based strategies to improve IBD outcomes. In practice, this means using data from the registry and related analyses to point toward clinical practices, care models, and healthcare delivery approaches that are associated with better results for patients. The anticipated outcome is actionable knowledge about what works in real-world settings, which can inform improvements in clinical management, public health approaches, and health system decision-making. Overall, the CDC frames the expected results as a way to enhance understanding of IBD's impact on overall health and to clarify how differences in clinical practice and healthcare delivery contribute to differences in outcomes.
Administratively, this is a discretionary funding opportunity from the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), listed under CFDA 93.945, with the activity category of Health. The funding instrument is a cooperative agreement, which typically implies substantial involvement by the funding agency during the project period compared with a standard grant mechanism. The award ceiling is $800,000, and the notice anticipates a single award (Expected Awards: 1), suggesting a single recipient or lead organization would be responsible for building and operating the registry and carrying out the associated analyses and strategy identification work.
Eligibility is broad and includes many types of entities across government, education, nonprofit, tribal, and private sectors. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other eligible entities as clarified in the opportunity materials. The opportunity was created on Nov 30, 2017, with an original closing date of Feb 09, 2018, and it specifies that electronic applications were due by 5:00 p.m. Eastern Time on the application due date.
Taken together, the opportunity is aimed at building national-quality surveillance and outcomes knowledge for IBD through a registry-based approach, while also generating practical insights into disparities and management strategies that can improve patient health outcomes and reduce the broader burden of IBD in the United States.Apply for RFA DP 18 001
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Etiology and Outcome of Inflammatory Bowel Disease" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.945.
- This funding opportunity was created on Nov 30, 2017.
- Applicants must submit their applications by Feb 09, 2018 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $800,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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