Opportunity Information: Apply for HT942526LRPIPA
The Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), is offering the FY26 Lupus Research Program (LRP) Impact Award (IPA) under funding opportunity number HT942526LRPIPA. This is a discretionary grant opportunity in the science and technology/research and development category (CFDA 12.420) aimed at supporting research that could substantially advance the field of lupus or meaningfully affect lupus disease outcomes. The central theme of this mechanism is high-risk, high-reward work where the payoff could be significant if the approach succeeds, with a strong emphasis on the potential for major impact rather than incremental progress.
Applications must directly address at least one of the designated FY26 LRP Impact Award focus areas. While the specific focus areas are not listed in the provided text, applicants should expect that alignment with those stated priorities will be a core review and eligibility factor. The mechanism is structured to encourage ambitious ideas, and it explicitly notes that preliminary data are encouraged but not required, which can make it a better fit for novel or less-established directions where early evidence is still emerging.
One important limitation is that clinical trials are not allowed under this funding mechanism. Proposed studies therefore need to be designed as preclinical, translational (without crossing into clinical trial activity), mechanistic, or other forms of non-trial research that still clearly connect to lupus impact. This restriction affects both study design and how outcomes are framed, so applicants should ensure the work does not meet common definitions of a clinical trial.
Eligibility is listed as unrestricted, meaning a broad range of applicant organizations may be able to apply, subject to standard federal grant rules and any additional requirements in the full announcement. The agency anticipates making about five awards. The opportunity was created on May 5, 2026, and the original closing date is August 24, 2026, so applicants should plan around that deadline and allow time for internal routing, registrations, and proposal development.
There are also limits on how many applications a single researcher can lead. An individual may serve as Principal Investigator on only one application per LRP award mechanism (specifically: Idea Award, Impact Award, Transformative Vision Development Award, and Transformative Vision Award). In practical terms, that means one person can be the PI on up to four FY26 LRP submissions total, but only one per mechanism, which is intended to prevent duplicative submissions while still allowing investigators to pursue different concepts across the program.
Finally, the award ceiling is not specified in the provided source data, so the maximum budget, period of performance, and other cost rules would need to be confirmed in the full funding announcement.Apply for HT942526LRPIPA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Lupus, Impact Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2026-05-05.
- Applicants must submit their applications by 2026-08-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Unrestricted.
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FY26 Lupus Research Program (LRP) Impact Award (IPA) - FAQs
What is this funding opportunity?
This opportunity is the FY26 Lupus Research Program (LRP) Impact Award (IPA), offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA). The funding opportunity number is HT942526LRPIPA. It is a discretionary grant in the science and technology/research and development category and is associated with CFDA 12.420.
What is the main goal of the LRP Impact Award?
The goal is to support research that could substantially advance the field of lupus or meaningfully affect lupus disease outcomes. The mechanism emphasizes the potential for major impact rather than incremental progress.
What type of research is this award designed to support?
This mechanism is built around high-risk, high-reward research, meaning the work can be ambitious and less conventional as long as the potential payoff is significant if the approach succeeds. Projects should still be clearly connected to lupus impact.
Do applications have to align with specific focus areas?
Yes. Applications must directly address at least one of the designated FY26 LRP Impact Award focus areas. The focus areas themselves are not included in the provided information, but alignment with those priorities is expected to be a core eligibility and review factor.
Are preliminary data required?
No. Preliminary data are encouraged but not required. This makes the mechanism potentially suitable for novel directions where early evidence is still emerging.
Are clinical trials allowed under this funding mechanism?
No. Clinical trials are not allowed under the FY26 LRP Impact Award mechanism.
If clinical trials are not allowed, what kinds of studies can be proposed?
Proposed studies should be designed as non-clinical-trial research such as preclinical, mechanistic, or translational work that does not cross into clinical trial activity, while still maintaining a clear connection to lupus impact and outcomes.
How should applicants handle the clinical trial restriction when designing the project?
Applicants should ensure the proposed work does not meet common definitions of a clinical trial. This affects both study design and how outcomes are framed, so project activities should remain within non-trial research boundaries.
Who is eligible to apply?
Eligibility is listed as unrestricted, which indicates a broad range of applicant organizations may be able to apply, subject to standard federal grant rules and any additional requirements included in the full funding announcement.
How many awards does the agency expect to make?
The agency anticipates making about five awards.
When was this opportunity posted?
The opportunity was created on May 5, 2026.
What is the application deadline?
The original closing date is August 24, 2026. Applicants should plan ahead and leave time for internal routing, registrations, and proposal development.
Is there a limit on how many applications one person can submit as Principal Investigator (PI)?
Yes. An individual may serve as PI on only one application per LRP award mechanism. The mechanisms named are: Idea Award, Impact Award, Transformative Vision Development Award, and Transformative Vision Award.
How many total FY26 LRP submissions can one person lead as PI across mechanisms?
Based on the provided information, one person could be the PI on up to four FY26 LRP submissions total, as long as they submit no more than one per mechanism.
Why does the program limit PI submissions per mechanism?
The limit is intended to prevent duplicative submissions while still allowing investigators to pursue different concepts across the broader FY26 LRP program.
What is the maximum award amount (budget ceiling)?
The award ceiling is not specified in the provided information. The maximum budget, period of performance, and other cost rules would need to be confirmed in the full funding announcement.
Where can applicants find details like the focus areas, budget limits, and performance period?
Those details are not included in the provided text and would need to be obtained from the full funding announcement for HT942526LRPIPA.
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