NICHD Research Project Grant (R01 - Clinical Trial Required) | PA 18 480

Opportunity Information: Apply for PA 18 480

The NICHD Research Project Grant (R01 - Clinical Trial Required) is a discretionary NIH funding opportunity (Funding Opportunity Number: PA 18 480; CFDA: 93.865) administered by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. It uses the R01 research project grant mechanism to support investigator-driven clinical trials that align with NICHDs mission areas, which broadly include research to understand human development, improve reproductive health, enhance the lives of children and adolescents, and optimize the abilities of individuals through rehabilitation and related health research. The key feature of this particular announcement is that it is specifically intended for applications that include a clinical trial, meaning the proposed work must involve prospectively assigning human participants to one or more interventions to evaluate effects on health-related biomedical or behavioral outcomes, consistent with NIH definitions.

This opportunity is open to a wide range of applicant organizations across the public, private, nonprofit, and academic sectors. Eligible applicants include state, county, city or township, and special district governments, as well as independent school districts and public housing authorities (including Indian housing authorities). Higher education applicants may be public/state-controlled or private institutions of higher education. The program also allows applications from nonprofit organizations, whether they hold 501(c)(3) status or not (so long as they are not institutions of higher education), and it includes for-profit organizations other than small businesses, in addition to small businesses themselves. Tribal eligibility is broad: federally recognized Native American tribal governments are eligible, and Native American tribal organizations that are not federally recognized are also included. Beyond these categories, the announcement explicitly names additional eligible entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). Faith-based and community-based organizations may apply, and the opportunity also extends to eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations), reflecting a willingness to support research teams and trial settings that best fit the scientific and public health need.

From an administrative standpoint, the opportunity is categorized under Health, Income Security and Social Services and is offered as a grant funding instrument. The source data indicates an original closing date of 2021-05-07 and a creation date of 2017-12-06. No award ceiling or expected number of awards is specified in the provided record, which is common for many NIH announcements where award size and volume depend on application quality, programmatic priorities, and available appropriations rather than a fixed cap stated in the synopsis.

In practical terms, this announcement is meant for applicants proposing rigorous, well-justified clinical trials under the traditional R01 structure, where the research question, design, participant protections, feasibility, and analytic plan are all central to the evaluation. Because it is an NICHD opportunity, competitiveness typically depends on how directly the clinical trial addresses NICHD-relevant health issues and populations, how sound and ethical the trial design is, and whether the investigative team and environment can realistically execute the study and generate results that matter for clinical care, public health practice, or future research.

• The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "NICHD Research Project Grant (R01 - Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
• This funding opportunity was created on 2017-12-06.
• Applicants must submit their applications by 2021-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PA 18 480

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